A map of relationships between uterine natural killer cells and progesterone receptor expressing cells during mouse pregnancy
MJ Oh, BA Croy - Placenta, 2008 - Elsevier
Uterine natural killer (uNK) cells appear in implantation sites with decidualization. Initially,
they are rare, highly proliferative cells that become abundant by midgestation and then die
abruptly. Steps regulating the cyclic appearance of uNK cells are incompletely defined.
Although progesterone (P4) has an essential role, mature uNK cells of women and mice lack
progesterone receptors (PR). Immunohistochemical studies suggest that mouse PR− uNK
cells may co-localize with PR+ stromal cells while human PR− uNK cells co-localize with …
they are rare, highly proliferative cells that become abundant by midgestation and then die
abruptly. Steps regulating the cyclic appearance of uNK cells are incompletely defined.
Although progesterone (P4) has an essential role, mature uNK cells of women and mice lack
progesterone receptors (PR). Immunohistochemical studies suggest that mouse PR− uNK
cells may co-localize with PR+ stromal cells while human PR− uNK cells co-localize with …
